BPA – now a potential saboteur of breast cancer treatment

By Barbara Kessler

The news on bisphenol A or BPA just doesn’t get better. The chemical, used to make plastic baby bottles and food can liners, could deliver a double-whammy to women, paving the way for breast cancer, and then boomeranging back to interfere with the treatment for cancer recovery.

A study by University of Cincinnati scientists released this week found that BPA exposure may reduce the effectiveness of chemotherapy treatments for breast cancer patients.

Researchers found that this man-made chemical – already implicated as a potential trigger in breast cancer because it is structurally similar to the estrogenic DES – induced a group of proteins in the body to protect breast cancer cells from the chemotherapy.

Resistance to chemotherapy is already a “major problem for cancer patients, especially those with advanced metastatic disease,” said UC’s Nira Ben-Jonathan, a professor of cell biology who’s been studying BPA for more than a decade.